
Limited Use
Select this option to continue as a guest or to order with a credit card at Corning's list price and register your Vat-exempt status.
Full Service
Select this option to view your account specific pricing or to order with a purchase order or credit card.
Corning® TransportoCells™ Human BSEP Vesicle, 5 mg/ mL, 0.5 mL
Product Number 453802(This is the suggested replacement for 453502).
Corning TransportoCells HEK293-derived ABC transporter vesicles express more human-like transporter proteins within the human cellular membrane. These HEK membrane vesicles have demonstrated a significantly higher uptake activity and lower background as compared with traditional insect cell-derived vesicles. The validated vesicle model could potentially improve in vitro to in vivo prediction because of the more in vivo-like recombinant proteins and membrane composition. The products can be used for drug transporter phenotyping, drug-drug interaction and toxicity studies, drug clearance prediction, and mechanistic studies of drug transport.
- Contain more in vivo-like recombinant proteins and membrane composition, thus providing the potential for a better in vitro to in vivo correlation
- Demonstrate a robust dynamic range with significantly higher uptake activity and lower background than insect cell expression systems
- Has been fully validated for substrate specificity, transporter kinetics, and inhibition profiles
- Support the USFDA, EMA, and ITC recommendations for the identification of drug transporters and transporter drug-drug interaction studies
This product is non-returnable. If you have any questions, please contact us immediately.
€628.25 per each
Less than 10 in Stock
Product Number | 453802 |
Qty./Pk | 1 / Pk |
Qty./Cs | 1 / Ea |
Brand | Corning® |
Species | Human |
Protein Concentration | 5 mg/mL |
Transporter | BSEP |
Shelf Life | 5 years |
Storage | -80°C |
- Quality Certificate - Lot No.9284001
- Quality Certificate - Lot No.9231001
- Quality Certificate - Lot No.9063003
- Quality Certificate - Lot No.8332004
- Quality Certificate - Lot No.8215002
- Quality Certificate - Lot No.6342017
- Quality Certificate - Lot No.1005002
- Quality Certificate - Lot No.0170001
- Quality Certificate - Lot No.0100001
- Quality Certificate - Lot No.0010001