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Corning® Microcarriers for Bioprocess Scale-up

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Corning microcarriers are designed to simplify your scale-up processes. The microcarriers are sterile, ready-to-use, and available in closed systems packaging to be used directly with bioreactors. Additionally, the microcarriers are surface-treated to enhance cell attachment, maximizing cell yield and viability.

Features

  • Consistency – USP Class VI polystyrene material provides a consistent platform
  • Performance – Corning microcarriers are offered untreated or with the following surface treatments:
    • Corning Synthemax® II substrate creates a synthetic surface on the microcarriers for stem cell expansion. For use with MSC and iPS/ES applications. (Animal Origin Free)
    • Corning CellBIND® surface treatment infuses the surface of the microcarriers with oxygen to improve cell attachment. (Animal Origin Free)
    • Collagen coating
  • Sterility Assurance Level (SAL) of 10⁻⁶
  • Nonpyrogenic
  • Available as closed system solutions

Product Specifications

  • Bead size: 125 µm to 212 µm
  • Density: 1.026 ± 0.004 g/cm³
  • cm²/gram: 360

Vials and Closed System Packaging

Corning microcarriers are available sterile and ready to use in 10 g vials. This format provides flexibility to select the amount of beads to use.

During the mature phase of process development and into manufacturing, closed system packaging would be necessary to maintain sterility and ease bioreactor loading. Corning microcarriers are also available in off-the-shelf and custom closed systems packaging. Tubing, connectors, and materials are customizable based on individual needs.