Laminin (LM), a major component of basement membranes, is a multifunctional glycoprotein that is used as a substrate to culture and maintain differentiated function of a wide variety of cells. Laminin has been shown in culture to stimulate neurite outgrowth, promote cell attachment, chemotaxis, cell differentiation, and neuronal survival.
Applications include:
- Promotion of cell attachment and spreading
- Induction of cell differentiation and neurite outgrowth
- Increases proliferation of myoblasts
- Studies of effects of laminin on cell behavior
- Cell adhesion assays
Source
Quality Control
- Tested for ability to initiate differentiation (neurite outgrowth) of NG-108 rat glioma/mouse neuroblastoma cells
- Tested and found negative for bacteria and fungi
- Laminin purity >90% by SDS-PAGE (contains entactin)
Storage