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Corning® TransportoCells™ Human BCRP Vesicle, 5 mg/ mL, 0.5 mL

Product Number 453804
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This is suggested replacement for 453271).

Corning TransportoCells HEK293-derived ABC transporter vesicles express more human-like transporter proteins within the human cellular membrane. These HEK membrane vesicles have demonstrated a significantly higher uptake activity and lower background as compared with traditional insect cell-derived vesicles. The validated vesicle model could potentially improve in vitro to in vivo prediction because of the more in vivo-like recombinant proteins and membrane composition. The products can be used for drug transporter phenotyping, drug-drug interaction and toxicity studies, drug clearance prediction, and mechanistic studies of drug transport.

  • Contain more in vivo-like recombinant proteins and membrane composition, thus providing the potential for a better in vitro to in vivo correlation
  • Demonstrate a robust dynamic range with significantly higher uptake activity and lower background than insect cell expression systems
  • Has been fully validated for substrate specificity, transporter kinetics, and inhibition profiles
  • Support the USFDA, EMA, and ITC recommendations for the identification of drug transporters and transporter drug-drug interaction studies

This product is non-returnable. If you have any questions, please contact us immediately.


€ 609,95 per each

Out of Stock

Details
Product Number   453804
Qty./Pk   1 / Pk  
Qty./Cs   1 / Ea  
Brand   Corning®  
Species   Human  
Protein Concentration   5 mg/mL  
Transporter   BCRP  
Shelf Life   5 years  
Storage   -80°C  
Specifications Documents