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Corning® BioCoat® Collagen IV-coated Plates

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Type IV Collagen is a ubiquitous component in basement membranes and provides the major structural support for this matrix. When the Collagen IV meshwork is assembled, it provides a scaffold for the assembly of other basement membrane components through interactions with laminin, entactin/nidogen, and heparan sulfate proteoglycan. Collagen IV is useful as a substrate for growth of epithelial, endothelial, muscle, and nerve cells. Collagen plays a role in the regulation of cell growth, differentiation and adhesion, as well as tissue formation.

Applications include:

  • Promotion of cell attachment and spreading
  • Cell differentiation and neurite outgrowth
  • Increased proliferation of PC12 cells
  • Studies of effects of collagen IV on cell behavior
  • Cell adhesion assays

Source

  • Engelbreth-Holm-Swarm (EHS) lathrytic mouse tumor

Quality Control

  • Tested for ability to initiate differentiation (neurite outgrowth) of NG-108 rat glioma/mouse neuroblastoma cells
  • Tested and found negative for bacteria and fungi
  • Collagen IV purity >90% by SDS-PAGE

Storage

  • 2°C to 8°C. Do not freeze.

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Products

Product Number Product Name Qty./Pk Qty./Cs Brand Price Unit Size
354428 Corning® BioCoat® Collagen IV 6-well Clear Flat Bottom TC-treated Multiwell Plate, with Lid, 5/Case   1 / Pk     5 / Cs     Corning®   N/A per case
354430 Corning® BioCoat® Collagen IV 24-well Clear Flat Bottom TC-treated Multiwell Plate, with Lid, 5/Case   1 / Pk     5 / Cs     Corning®   N/A per case