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Corning® Gentest™ HLM, ~20-Donor Pool, Mixed Gender, 0.5 mL

Product Number 452161
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This HLM product is targeted to meet a calculated mean of the average liver profile for the big five CYPs based on ~140 tested livers for improved prediction and scaling for these 5 enzymes (CYP1A2, 2C9, 2C19, 2D6, and 3A4). HLMs from pre-selected donors are mixed at ratios to give the desired activities for the big five P450s. The product is also characterized for other important metabolizing CYPs, UGTs, and other enzymes

Features/Benefits:

  • Pool of ~20 pre-selected donors mixed at ratios to give the desired activities for the big five P450s (CYP1A2, 2C9, 2C19, 2D6, and 3A4)
  • The activities for the big five P450s are targeted to meet a calculated mean of the average liver profile based on ~140 tested livers for improved prediction and scaling for these 5 enzymes
  • Characterized for additional important cytochrome P450, UGTs and other enzymes.
  • Large lot size available
  • Tissues are sourced from US-based Organ Procurement Organizations, meeting high ethical standards with strict traceability
  • Manufactured by adhering to high safety standards including serological testing prior to acceptance, followed by PCR testing for HIV I/II, Hepatitis B, Hepatitis C, HTLV 1/2 (human T-cell leukemia virus) pathogens, and CMV (cytomegalovirus)
  • Available Size: 0.5 mL
  • Protein Concentration: 20 mg/ mL in 250 mM Sucrose
  • Shelf life: N/A (this product is stable for more than 10 years when stored properly)


To obtain characterization data for a specific lot and donor demographic information, please contact corning scientific support at Scientificsupport@corning.com


This product is non-returnable. If you have any questions, please contact us immediately.


$118.08 per each

In Stock

Details
Product Number   452161
Qty./Pk   1 / Pk  
Qty./Cs   1 / Ea  
Brand   Corning®  
Size   0.5 mL  
Species   Human  
Protein Concentration   20 mg/mL  
Storage   -80°C  
Gender   Mixed gender  
Fraction Types   Microsomes  
Specifications Documents