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Corning® Supersomes™ Rat CYP2C11 + Reductase + b5, 0.5 nmol

Product Number 456531
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Discontinued: 456531; Suggested Replacement: None.

Recombinant enzyme prepared from insect cells infected with baculovirus containing desired cDNAs

Rat CYP2C enzymes are the most abundant cytochromes P450 in untreated rat livers, in contrary to human livers where CYP3A enzymes are the most abundant cytochrome P450. Similar to other species, there are multiple CYP2C enzymes expressed in rat livers. However, unlike in human, CYP2C enzymes in rat demonstrate sex-specific expression. For example, CYP2C11 and CYP2C13 are expressed in the livers of males while CYP2C12 is expressed in females. CYP2C6 is not sex specific.

Rat CYP2C11 hydroxylates testosterone in the 2α and 16α positions, and is not reported to be inducible.

 

  • Contains Rat Oxidoreductase and human cytochrome b₅
  • Available size: 0.5 nmole P450 in 0.5 mL
  • Protein concentration: Available in batch data sheet. Contact Corning Scientific support to obtain the information.

 


This product is non-returnable. If you have any questions, please contact us immediately.


$202.27 per each

Less than 10 in Stock

Details
Product Number   456531
Qty./Pk   1 / Pk  
Qty./Cs   1 / Ea  
Brand   Corning®  
Size   0.5 nmol  
Species   Rat  
Enzyme Type   P450  
Protein Concentration   Lot-dependent  
Storage   -80°C  
Cellular Location   Microsome  
Specifications Documents