text.skipToContent text.skipToNavigation

 IMPORTANT UPDATE:  Some items may be delayed in shipping or out of stock due to extremely high demand.

Corning® Supersomes™ Human CYP2B6 + Oxidoreductase, 0.5 nmol

Product Number 456210
E-mail


Recombinant enzyme prepared from insect cells infected with baculovirus containing desired cDNAs

CYP2B6 is variably expressed in HLMs. CYP2B6 is involved in the metabolism of several drugs which include bupropion, efavirenz, S-mephenytoin (N-demethylation), and the anesthetics methoxyflurane and propofol. The structurally-related anticancer drugs cyclofosphamide and ifosfamide are activated by CYP2B6. CYP2B6 is capable of activating carcinogens such as aflatoxin B1 and the tobacco smoke-derived nitrosamine, NNK, to the cytotoxic species. CYP2B6 protein levels can be induced several fold in the liver by ligands of CAR and PXR receptors (e.g. phenobarbital, rifampin, and phenytoin).

  • Contains Human Oxidoreductase, but not cytochrome b₅
  • Available size: 0.5 nmole P450 in 0.5 mL
  • Protein concentration: Available in batch data sheet. Contact Corning Scientific support to obtain the information.



This product is non-returnable. If you have any questions, please contact us immediately.


$176.99 per each

Out of Stock

Details
Product Number   456210
Qty./Pk   1 / Pk  
Qty./Cs   1 / Ea  
Brand   Corning®  
Size   0.5 nmol  
Species   Human  
Enzyme Type   P450  
Protein Concentration   Lot-dependent  
Storage   -80°C  
Cellular Location   Microsome  
Specifications Documents