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Corning® Gentest™ ABC Transporter Vesicles

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Corning Gentest ABC transporter inside-out vesicles are used in in vitro direct uptake assays to evaluate whether a drug candidate is a substrate or inhibitor for transporters. This information can help to predict the interactions between drug compounds and efflux transporters. ABC transporter vesicles are an ideal transporter model over cell-based assays for compounds unable to penetrate the plasma membrane by simple diffusion.

  • Prepared from recombinant baculovirus-infected insect cells
  • Direct measurement of transporter-mediated drug uptake
  • Use in drug uptake assays for radiolabeled or non-radiolabeled compounds

Corning also offers transporter vesicle kits to use with the vesicle products. The kits contain all necessary buffers and chemicals for performing 200 assays, providing convenience and reducing the time needed for reagent preparation.



Arg = Arginine.


Products

Product Number Product Name Qty./Pk Qty./CS Brand Price Unit Size
453271 Corning® Gentest™ Human BCRP (Arg482) Vesicles, 0.5 mL   1 / Pk     1 / Ea     Corning®   per each
453345 Corning® Gentest™ Rat Bcrp Vesicles, 0.5 mL   1 / Pk     1 / Ea     Corning®   per each
453450 Corning® Gentest™ Human MRP2 Vesicles, 0.5 mL   1 / Pk     1 / Ea     Corning®   per each
453500 Corning® Gentest™ Negative Control Vesicles, 0.5 mL   1 / Pk     1 / Ea     Corning®   per each
453501 Corning® Gentest™ Rat Bsep Vesicles, 0.5 mL   1 / Pk     1 / Ea     Corning®   per each
453502 Corning® Gentest™ Human BSEP Vesicles, 0.5 mL   1 / Pk     1 / Ea     Corning®   per each
453520 Corning® Gentest™ Human MRP3 Vesicles, 0.5 mL   1 / Pk     1 / Ea     Corning®   per each
453523 Corning® Gentest™ Rat Mrp2 Vesicles, 0.5 mL   1 / Pk     1 / Ea     Corning®   per each